51. “A para- to meta-isomerization of phenols” Edelmann, S.; Lumb, J.-P. Nat. Chem. 2024, doi: 10.1038/s41557-024-01512-1.
50. ‘‘Mechanisms for radical reactions initiating from N-hydroxyphthalimide esters’’ Azpilcueta-Nicolas, C. R.; Lumb, J.-P. Beilstein J. Org. Chem. 2024, doi: 10.3762/bjoc.20.35
49. ‘‘Mimicking Non-Canonical Radical Cyclizations in the Synthesis of Dibenzocyclooctadiene Natural Products’’ Carroll-Pöhls, M.; Lumb, J.-P. ChemCatChem 2024, doi: 10.1002/cctc.202301290
48. “Indole-5,6-quinones display hallmark properties of eumelanin” Wang, X.; Kinziabulatova, L.; Bortoli, M.; Manickoth, A.; Barilla, M.A.; Huang, H.; Blancafort, L.; Kohler, B.; Lumb, J.-P. Nat. Chem. 2023, doi.10.1038/s41557-023-01175-4.
47. “Dearomatization of Biaryls through Polarity Mismatched Radical Spirocyclization” Azpilcueta-Nicolas, C. R.; Meng, D.; Edelmann, S.; Lumb, J.-P. Angew. Chem. Int. Ed. 2023, 62, e202215422.
46. “A Bioinspired Synthesis of 1,4-Benzothiazines by Selective Addition of Sulfur Nucleophiles to ortho-Quinones” Halloran, M. W.; Li, E.; Esguerra, K. V. N.; Lumb, J.-P. J. Org. Chem. 2023, 88, 2561-2569.
45. “Mimicking Oxidative Radical Cyclizations of Lignan Biosynthesis Using Redox-Neutral Photocatalysis" Huang, Z.; Lumb, J.-P. Nat. Chem 2021, 13, 24-32.
Featured in News and Views: “Making Light Work of Lignan Synthesis” Thach, D. Q.; Maimone, T. J. Nat. Chem. 2021, 13, 7-9.
And check out Zheng Huang’s Behind the Paper Blog Post discussing this work.
44. “Total Synthesis of (S)-Cularine via Nucleophilic Substitution on a Catechol” Huang, Z.; Ji, X.; Lumb, J.-P. Org. Lett. 2021, 23, 236-241.
43. "Regioselective Synthesis of Polyfunctional Arenes by a 4-Component Catellani Reaction" Wang, J.; Qin C.; Lumb, J.-P.; Luan, X. Chem 2020, 6, 2097-2109.
42. “Synthesis of 1,2-Dihydroisoquinolines by a Modified Pomeranz-Fritsch Cyclization" Ji, X.; Huang, Z.; Lumb, J.-P. J. Org. Chem. 2020, 85, 1062-1072.
41. "Total Synthesis of (S,S)-Tetramethylmagnolamine via Aerobic Desymmetrization" Huang, Z.; Ji, X.; Lumb, J.-P. Org. Lett. 2019, 21, 9194-9197.
40. “Ex Vivo Expansion of Skeletal Muscle Stem Cells with a Novel Small Compound Inhibitor of eIF2α Dephosphorylation” Lean, G.; Halloran, M. W.; Marescal, O.; Jamet, S.; Lumb J.-P.; Crist, C. Regen. Med. Front. 2019,1:e190003.
39. “Catalytic Aerobic Cross-Dehydrogenative Coupling of Phenols and Catechols” Xu, W.; Huang, Z.; Xiang, J.; Lumb, J.-P. ACS Catal. 2019, 9, 3800-3810.
38. “Phenol-Directed C–H Functionalization” Huang, Z.; Lumb, J.-P. ACS Catal. 2019, 9, 521-555.
37."Cu(III)-Mediated Aerobic Oxidations" Esguerra, K. V. N.; Lumb, J.-P. Synthesis 2019, 51, 334-358.
36. “Recent Applications of Diazirines in Chemical Proteomics" Halloran, M. W.; Lumb, J.-P. Chem. Eur. J. 2019, 25, 4885-4898.
35. “A Bioinspired Synthesis of Polyfunctional Indoles" Huang, Z.; Kwon, O.; Huang, H.; Fadli, A.; Marat, X.; Moreau, M.; Lumb, J.-P. Angew. Chem. Int. Ed. 2018, 57, 11963-11967.
34. “Selectivity in the Aerobic Dearomatization of Phenols: Total Synthesis of Dehydronornuciferine by Chemo- and Regioselective Oxidation" Esguerra, K. V. N.; Lumb, J.-P. Angew. Chem. Int. Ed. 2018, 57, 1514-1518.
33. "Catalytic Aerobic Oxidation of Halogenated Phenols" Esguerra, K. V. N.; Fall, Y.; Lumb, J.-P. Inorg. Chim. Acta. 2018, 481, 197-200.
32. "Stopping Aerobic Oxidation in Its Tracks: Chemoselective Synthesis of Benzaldehydes from Methylarenes" Lumb, J.-P. Angew. Chem. Int. Ed. 2017, 56, 9276-9277.
31. “A Bioinspired Catalytic Aerobic Functionalization of Phenols: Regioselective Construction of Aromatic C–N and C–O Bonds” Esguerra, K. V. N.; Lumb, J.-P. ACS Catalysis, 2017, 7, 3477-3482.
30. "Synthesis of ortho-Azophenols by Formal Dehydrogenative Coupling of Phenols and Hydrazines or Hydrazides" Esguerra, K. V. N.; Lumb, J.-P. Chem. Eur. J. 2017, 23, 8596-8600. See the Inside Front Cover.
29. "A Chlorine-Free Protocol for Processing Germanium" Glavinović, M.; Krause, M.; Baines, K.; Friščić, T.; Lumb, J.-P. Sci. Adv. 2017, 3, e1700149.
28. “Development of 3,5-di-tert-Butylphenol as a Model Substrate for Biomimetic Aerobic Copper Catalysis” Kwon, O,; Esguerra, K. V. N.; Glazerman, M.; Petitjean, L.; Xu, Y.; Ottenwaelder, X.; Lumb, J.-P. Synlett, 2017, 28, 1548-1553.
Contribution to the Synlett Cluster on Aerobic Catalysis.
27. “A Unified Synthesis of 1,2-Oxy Amino Arenes via a Bio-Inspired Phenol / Amine Coupling” Esguerra, K.V.N.; Xu, W.; Lumb, J.-P. Chem 2017, 2, 533–549.
26. “Second-Order Biomimicry: In Situ Oxidative Self-Processing Converts Copper(I)/Diamine Precursor into a Highly Active Aerobic Oxidation Catalyst” McCann, S.; Lumb, J.-P.; Arndtsen, B.; Stahl, S. ACS Cent. Sci. 2017, 3, 314-321.
25. "Simple Copper Catalysts for the Aerobic Oxidation of Amines: Selectivity Control by the Counterion" Xu, B.; Hartigan, E. M.; Feula, G.; Huang, Z.; Lumb, J.-P.; Arndtsen, B. A. Angew. Chem. Int. Ed. 2016, 55, 15802-15806.
24. "A Catalyst-Controlled Aerobic Coupling of ortho-Quinones and Phenols Applied to the Synthesis of Aryl Ethers" Huang, Z.; Lumb, J.-P. Angew. Chem. Int. Ed. 2016, 55, 11543-11547.
23. "Redox-Promoted Associative Assembly of Metal-Organic Materials" Glavinovic, M.; Qi, F.; Katsenis, A. D.; Friscic, T.; Lumb, J.-P. Chem. Sci. 2016, 7, 707-712.
22. "A Bio-Inspired Synthesis of Oxindoles by Catalytic Aerobic Dual C-H Functionalization of Phenols" Huang, Z.; Askari, M. S.; Esguerra, K. V. N.; Dai, T.-Y.; Kwon, O.; Ottenwaelder, X.; Lumb, J.-P. Chem. Sci. 2016, 7, 358-369.
21. "Adapting Melanogenesis to a Regioselective C–H Functionalization of Phenols" Esguerra, K. V. N.; Lumb, J.-P. Synlett. 2015, 26, 2731-2738.
20. "A Biomimetic Mechanism for the Copper Catalyzed Aerobic Oxygenation of 4-tert-Butylphenol" Askari, M. S.; Esguerra, K. V. N.; Lumb, J.-P.; Ottenwaelder, X. Inorg. Chem. 2015, 54, 8665-8672.
19. "A Divergent and Selective Synthesis of ortho- and para-Quinones From Phenols" Huang, Z; Kwon, O; Esguerra, K. V. N.; Lumb, J.-P. Tetrahedron. 2015, 71, 5871-5885.
18. "Catalytic Aerobic Oxidation of Phenols to ortho-Quinones with Air-Stable Copper Precatalysts" Askari, M.S.; Rodriguez-Salano, L. A.; Proppe, A.; McAllister, B.; Lumb, J.-P.; Ottenwaelder, X. Dalton Trans. 2015, 44, 12094-12097.
17. "A TEMPO-Free Copper Catalyzed Aerobic Oxidation of Alcohols" Xu, B.; Lumb, J.-P.; Arndtsen, B. A. Angew. Chem. Int. Ed. 2015, 54, 4208-4211.
16. "A Bio-Inspired Total Synthesis of Tetrahydrofuran Lignans" Albertson, A.K.F.; Lumb, J.-P. Angew. Chem. Int. Ed. 2015, 54, 2204-2208.
15. "Controlling the Catalytic Aerobic Oxidation of Phenols" Esguerra, K. V. N.; Fall, Y.; Petitjean, L.; Lumb, J.-P. J. Am. Chem. Soc. 2014, 136, 7662-7668.
14. "A Biomimetic Catalytic Aerobic Functionalization of Phenols" Esguerra, K. V. N.; Fall, Y.; Lumb, J.-P. Angew. Chem. Int. Ed. 2014, 53, 5877-5881.
Postdoctoral and Graduate Work
13. “Synthesis of a 1,3-Bridged Macrobicyclic Enyne via Chemoselective Cycloisomerization Using Palladium-catalyzed Alkyne-Alkyne Coupling.” Trost, B.M.*; Masters, J. T.; Le Vaillant, F.; Lumb, J.-P. J. Org. Chem. 2016, 81, 10023–10028.
12. "Asymmetric Synthesis of Chiral b-Alkynyl Carbonyl and Sulfonyl Derivatives via Sequential Palladium and Copper Catalysis.” Trost, B.M.; Taft, B.R.; Masters, J. T.; Lumb, J.-P. Chem. Sci. 2016, 7, 6217-6231.
11. “Asymmetric Synthesis of Chiral Cycloalkenone Derivatives via Palladium Catalysis.” Trost, B.M.; Masters, J. T.; Lumb, J.P.; Fateen, D. Chem. Sci. 2014, 5, 1354.
10. “A New Strategy for the Synthesis of Chiral β-Alkynyl Esters via Sequential Palladium and Copper Catalysis.” Trost, B.M.; Taft, B.R.; Masters, J. T.; Lumb, J. P. J. Am. Chem. Soc. 2011, 133, 8502.
9. “An Atom-Economic Synthesis of Nitrogen Heterocycles from Alkynes.” Trost, B. M.; Lumb, J. P.; Azzarelli, J. M. J. Am. Chem. Soc. 2011, 133, 740.
8. “Total synthesis of Exiguamines A and B Inspired by Catecholamine Chemistry.” Sofiyev, V.; Lumb, J. P.; Volgraf, M.; Trauner, D. Chem. Eur. J. 2012. 26, 4999.
7. “Theoretical Investigation of the Rubicordifolin Cascade.” Lumb, J.P.*; Krinsky, J. L.; Trauner, D. Org. Lett. 2010, 12, 5162. (*Corresponding Author)
6. “ortho-Quinone Methides from para-Quinones: Total Synthesis of Rubioncolin B.” Lumb, J. P.; Choong, K. C.; Trauner, D. J. Am. Chem. Soc. 2008, 130, 9230.
5. “Biomimetic Synthesis of the IDO Inhibitors Exiguamine A and B.” Volgraf, M.; Lumb, J. P.; Brastianos, H. C.; Carr, G.; Chung, M. K. W.; Munzel, M.; Mauk, A. G.; Andersen, R. J.; Trauner, D. Nature Chemical Biology, 2008, 4, 535.
4. “Pericyclic Reactions of Prenylated Naphthoquinones: Biomimetic Synthesis of Mollugin and Microphyllaquinone.” Lumb, J. P.; Trauner, D. Org. Lett. 2005, 7, 5865.
3. “Biomimetic Synthesis and Structure Elucidation of Rubicordifolin, a Cytotoxic Natural Product from Rubia cordifolia.” Lumb, J. P.; Trauner, D. J. Am. Chem. Soc. 2005, 127, 2870.
2. “Polyhydroxylated aziridinylcyclopentanes as glycomimetics: A new competitive inhibitor of alpha-mannosidase.” Schoenfeld, R.; Lumb, J. P.; Ganem, B. Tetrahedron Lett., 2001, 42, 6447.
1. “Total synthesis of mololipids: A new series of anti-HIV Moloka'iamine derivatives.” Schoenfeld, R.; Lumb, J. P.; Ganem, B. Bioorg. Med. Chem. Lett., 2000, 10, 2679.